tag:blogger.com,1999:blog-8212356.post8479407327428859894..comments2023-11-19T00:42:48.156-08:00Comments on balancing life: All in the gutSunilhttp://www.blogger.com/profile/07776658071546232685noreply@blogger.comBlogger10125tag:blogger.com,1999:blog-8212356.post-47606304326393078452009-02-25T21:20:00.000-08:002009-02-25T21:20:00.000-08:00Once I played Rom, I did not know how to get stron...Once I played Rom, I did not know how to get strong, someone told me that you must have <A HREF="http://www.runesofmagicgold.us/" REL="nofollow">Rom Gold</A>. He gave me some <A HREF="http://www.runesofmagicgold.us/" REL="nofollow">Runes of Magic Gold</A>, he said that I could <A HREF="http://www.runesofmagicgold.us/" REL="nofollow">buy Rom Gold</A>, but I did not have money, then I played it all my spare time. From then on, I got some <A HREF="http://www.runesofmagicgold.us/" REL="nofollow">Runes of Magic money</A>, if I did not continue to play it, I can sell <A HREF="http://www.runesofmagicgold.us/" REL="nofollow">cheap Runes of Magic Gold</A>to anyone who want.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8212356.post-68801022749785807672007-02-16T06:58:00.000-08:002007-02-16T06:58:00.000-08:00hehe...good and profound question!hehe...good and profound question!Wavefunctionhttps://www.blogger.com/profile/14993805391653267639noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-12246048147670181652007-02-16T05:37:00.000-08:002007-02-16T05:37:00.000-08:00hmm.....there may be some truth in that, and it is...hmm.....there may be some truth in that, and it is possible.<BR/><BR/>So, would you rather die by the time you are 50?Sunilhttps://www.blogger.com/profile/07776658071546232685noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-80155701462044257112007-02-15T10:19:00.000-08:002007-02-15T10:19:00.000-08:00Well, some people see cancer and AD as inevitable ...Well, some people see cancer and AD as inevitable disorders that arise because of our increased life span. They say that we are living an abnormal life span; for all animals, the mean lifespan is more or less prportional to their reproductive lifespan. Not so in the case of humans, where we have increased the gap between the two with better lifestyles and drugs. So they say that it is inevitable that problems like cancer and AD will afflict us; our cells are not designed for such a long lifespan. It's an interesting theory.Wavefunctionhttps://www.blogger.com/profile/14993805391653267639noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-35430620611963275652007-02-15T05:45:00.000-08:002007-02-15T05:45:00.000-08:00hmm.....not sure I follow you here. Are you sayin...hmm.....not sure I follow you here. Are you saying cancer and AD (I assume AD is Alzheimer's disease) are human inventions?<BR/><BR/>Cancer has been around for a long, long time....and cancerous mutations in cells arise from a lot of causes, many of which are perfectly natural. And AD....is most often an aging related process...and the amyloid cascade hypothesis (currently the most accepted reason for the cause and progress of AD) doesn't have clear causes yet. It is likely that there would have been many AD patients in the past if people lived that long, but average lifespans a hundred years ago was only some 45 years...<BR/><BR/>But I completely agree that there is no "need" for drugs for some "illnesses" like obesity, which are better treated with diet and exercise.Sunilhttps://www.blogger.com/profile/07776658071546232685noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-5730006814606745142007-02-14T06:49:00.000-08:002007-02-14T06:49:00.000-08:00Sometimes I think that drug-discovery is futile, s...Sometimes I think that drug-discovery is futile, since we are fighting diseases of our own inventions!! Especially cancer and AD. Sigh.Wavefunctionhttps://www.blogger.com/profile/14993805391653267639noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-5388300588300936472007-02-13T19:38:00.000-08:002007-02-13T19:38:00.000-08:00ashutosh.....the authors did propose exactly that....ashutosh.....the authors did propose exactly that. But I think its a bad idea. Firstly, their studies show a complex, two-way relationship between the % of bacteria of each type and body weight, as well as body weight with % of bacteria. So, by forcibly altering one, you may have some short term benifits, but there are bound to be some more complex feedback loops. And obesity (unless it is genetic) is usually a result of bad eating habits and a lack of exercise. So, a "pill" to cure obesity isn't really going to cure it....it'll just make people lazier. But yes....the possibility of a Firmicutes inhibitor is certainly there.<BR/><BR/>Kiran...you're right......we are all walking, talking ecosystems, and what's more surprising is that we know little about all the bacteria we are hosts to. An interesting aside is that the mitochondira in cells, essential for our survival, is thought to have been aquired a long, long, long time ago in the early evolution of eukaryotic cells....and may well have been a primitive, independent cell.<BR/><BR/>Ash....good for you, and CS rules!Sunilhttps://www.blogger.com/profile/07776658071546232685noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-42078317480014113272007-02-13T14:55:00.000-08:002007-02-13T14:55:00.000-08:00Sunil, I actually ends up with a research job at A...Sunil, I actually ends up with a research job at A&M. Interesting health policy and social science research, although CS can be a really boring place to live in!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8212356.post-75707543361410480342007-02-13T11:44:00.000-08:002007-02-13T11:44:00.000-08:00Check this one out: http://www.wired.com/news/tech...Check this one out: http://www.wired.com/news/technology/0,65252-0.html<BR/><BR/>Most of the cells in your body are not your own, nor are they even human. They are bacterial. From the invisible strands of fungi waiting to sprout between our toes, to the kilogram of bacterial matter in our guts, we are best viewed as walking "superorganisms," highly complex conglomerations of human cells, bacteria, fungi and viruses.Kiranhttps://www.blogger.com/profile/02404008369159416565noreply@blogger.comtag:blogger.com,1999:blog-8212356.post-10950455707804396912007-02-13T06:05:00.000-08:002007-02-13T06:05:00.000-08:00Maybe a Firmicutes specific inhibitor would be a n...Maybe a Firmicutes specific inhibitor would be a next step. Perhaps one which targets the butyrate producing enzyme...Wavefunctionhttps://www.blogger.com/profile/14993805391653267639noreply@blogger.com